GLOVERSVILLE, N.Y. -- It was 1936 when Jim Del Negro's father opened his pharmacy on South Main Street.

"My father, when he opened he treated the customers like gold, he'd go to the door and open the door when they came in and out. It was amazing," he said.

While much of the pharmacy world has changed, Del Negro's gold standard of service has stayed.

Even after the Del Negro brothers sold it to their pharmacists twenty years ago.

"It's not easy leaving such a great clientele, great pharmacy staff here," owner Tom Wojciehowski said.

But with retirement on his mind, and no one willing to take the reins, Wojciehowski says it was just the right time.

"It will be sad, I'm sure they'll be some tears shed. It will be a tough moment," he said.

Del Negro's was stable here on Main Street.

So it's no surprise many longtime Gloversville residents say losing the pharmacy is a hard pill to swallow.

"I probably couldn't see over the top of the counter," Paul Parillo, who's been coming here since he was a kid, said.

Today he picked-up his last batch of refills.

"The small hometown stores, and drug stores and grocery stores are just something of the past now," Parillo said.

Some of the staff and patient records are moving up the street to Rite Aid.

While the company has promised to continue deliveries and honor store accounts, there's still something about this place customers can't get anywhere else.